Microbiological transformation of enrofloxacin by the fungus Mucor ramannianus.
نویسندگان
چکیده
Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones. Cultures grown in sucrose-peptone broth were dosed with enrofloxacin. After 21 days, 22% of the enrofloxacin remained. Three metabolites were identified: enrofloxacin N-oxide (62% of the total absorbance), N-acetylciprofloxacin (8.0%), and desethylene-enrofloxacin (3.5%).
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عنوان ژورنال:
- Applied and environmental microbiology
دوره 66 6 شماره
صفحات -
تاریخ انتشار 2000